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Results for "

17-phenyl-trinor-pgf2

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

4

Peptides

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125774
    Bimatoprost acid

    17-phenyl trinor pgf2α

    		 Prostaglandin Receptor Others
    Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .
    Bimatoprost acid
  • HY-116161A
    17-Phenyl trinor PGF2α isopropyl ester

    		Prostaglandin Receptor Metabolic Disease
    17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
    17-Phenyl trinor PGF2α isopropyl ester
  • HY-125774S
    Bimatoprost acid-d4

    17-phenyl trinor pgf2α-d4

    		 Isotope-Labeled Compounds Others
    Bimatoprost acid-d4 (17-Phenyl trinor PGF2α-d4) is the deuterium labeled Bimatoprost acid .
    Bimatoprost acid-d4
  • HY-114867
    (15R)-Bimatoprost

    15(R)-17-phenyl trinor pgf2α ethyl amide

    		 Prostaglandin Receptor Endocrinology
    (15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide) is a prostaglandin analog used to study glaucoma and ocular hypertension. (15R)-Bimatoprost is an isomer of Bimatoprost with an inverted (β) hydroxyl group on C-15 .
    (15R)-Bimatoprost
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide
  • HY-116161
    Bimatoprost isopropyl ester

    		Drug Intermediate Cardiovascular Disease Others
    15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
    Bimatoprost isopropyl ester
  • HY-W746888
    17-Phenyl trinor prostaglandin F2α diethyl amide

    17-p-pgf2α-NEt2; 17-phenyl trinor pgf2α diethyl amide

    		 Prostaglandin Receptor Cardiovascular Disease
    17-Phenyl trinor prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is a PGF2α analog with hypotensive efficacy .
    17-Phenyl trinor prostaglandin F2α diethyl amide
  • HY-P3350
    LS-BF1

    		Bacterial Infection
    LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
    LS-BF1
  • HY-176096
    1α-Monohomo-17-phenyl trinor Prostaglandin F2α

    1α-Monohomo-17-phenyl trinor pgf2α

    		 Biochemical Assay Reagents Others
    1α-Monohomo-17-phenyl trinor Prostaglandin F2α (1α-Monohomo-17-phenyl trinor PGF2α) is a derivative of 17-phenyl trinor prostaglandin F2α ethyl amide. 1α-Monohomo-17-phenyl trinor Prostaglandin F2α is also an isomer of 17-phenyl trinor prostaglandin F2α methyl ester.
    1α-Monohomo-17-phenyl trinor Prostaglandin F2α
  • HY-176014
    17-Phenyl trinor prostaglandin F2α glycinamide

    17-phenyl trinor pgf2α glycinamide

    		 Drug Derivative Others
    17-phenyl trinor PGF2α glycinamide (17-Phenyl trinor PGF2α glycinamide) is a derivative of 17-phenyl trinor prostaglandin F2α ethyl amide .
    17-Phenyl trinor prostaglandin F2α glycinamide
  • HY-113778
    15-keto-17-phenyl trinor Prostaglandin F2α

    15-keto-17-phenyl trinor pgf2α

    		 Prostaglandin Receptor Endocrinology
    15-keto-17-phenyl trinor Prostaglandin F2α (15-keto-17-phenyl trinor PGF2α) is an F-series prostaglandin (PG) analog. The potential metabolite of 15-keto-17-phenyl trinor Prostaglandin F2α in animals is 15-keto PG. 15-keto PG can slightly reduce the intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto-17-phenyl trinor Prostaglandin F2α is a miotic agent in cats, reducing the pupil diameter by 8 mm at a dose of 5 μg/eye.
    15-keto-17-phenyl trinor Prostaglandin F2α
  • HY-172574
    8-iso-17-Phenyl trinor prostaglandin F2α

    8-iso-17-phenyl trinor pgf2α

    		 Drug Isomer Drug Derivative Neurological Disease
    8-Iso-17-phenyl trinor prostaglandin F2α (8-Iso-17-phenyl trinor PGF2), the C-8 epimer of Bimatoprost (HY-B0191), is a PGF2α (HY-12956) analog. Bimatoprost can be used in the research of glaucoma and high intraocular pressure.
    8-iso-17-Phenyl trinor prostaglandin F2α
  • HY-W746889
    17-Phenyl trinor prostaglandin F2α 1,15-lactone

    17-phenyl trinor pgf2α 1,15-lactone

    		 Drug Derivative Others
    17-Phenyl trinor prostaglandin F2α 1,15-lactone (17-Phenyl trinor PGF2α 1,15-lactone) is a 1,15 lactone of 17-Phenyl trinor prostaglandin F2α. 17-Phenyl trinor prostaglandin F2α is a metabolite of Dinoprost (HY-12956) .
    17-Phenyl trinor prostaglandin F2α 1,15-lactone
  • HY-116679
    17-trifluoromethylphenyl trinor Prostaglandin F2α

    17-Trifluoromethylphenyl trinor pgf2α

    		 Prostaglandin Receptor Endocrinology
    A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists.4 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic, with a potency equal to or greater than fluprostenol and cloprostenol.
    17-trifluoromethylphenyl trinor Prostaglandin F2α
  • HY-105168
    TAK 044

    		Endothelin Receptor Cardiovascular Disease
    TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
    TAK 044
  • HY-176011
    17-Phenyl trinor prostaglandin F2α glycinamide methyl ester

    17-phenyl trinor pgf2α glycinamide methyl ester

    		 Prostaglandin Receptor Endocrinology
    17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a derivative of Bimatoprost (HY-B0191) and a prostaglandin analog. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a human prostaglandin FP receptor agonist. 17-Phenyl trinor prostaglandin F2α glycinamide methyl ester has an ocular hypotensive effect and can be used in the study of ocular hypertension and glaucoma .
    17-Phenyl trinor prostaglandin F2α glycinamide methyl ester
  • HY-139121
    15(R)-17-Phenyl trinor Prostaglandin F2α

    15-epi Bimatoprost free acid; 15(R)-Bimatoprost free acid; 15(R)-17-phenyl trinor pgf2α

    		 Prostaglandin Receptor Endocrinology
    15(R)-17-Phenyl trinor Prostaglandin F2α (15-epi Bimatoprost free acid) is a prostaglandin F (FP) analog that acts as an ocular hypotensive agent. The free acid 17-Phenyl trinor Prostaglandin F2α is a potent FP receptor agonist. 15(R)-17-Phenyl trinor Prostaglandin F2α is the 15-epi or "unnatural" isomer of this active free acid metabolite and has reduced FP receptor agonist activity.
    15(R)-17-Phenyl trinor Prostaglandin F2α
  • HY-158782
    5-trans Bimatoprost acid

    		Others Metabolic Disease
    5-trans-17-phenyl trinor Prostaglandin F2α (5-trans-17-phenyl trinor PGF2α) is the 5-trans isomer of HY-B0191 Bimatoprost (17-phenyl trinor PGF2α).
    5-trans Bimatoprost acid
  • HY-P4948
    Coumarin-Phalloidin

    		Biochemical Assay Reagents Others
    Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
    Coumarin-Phalloidin

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