Caesalpiniaceae

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.

3-(4-Nitrophenyl)-1H-pyrazol-5(4H)-one is a natural product found in Caesalpinia sappan. Caesalpinia sappan contains various phytochemicals and is considered a plant with significant medicinal value.

Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist...

2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia.

Rubrofusarin 6-O-β-D-glucopyranoside, the glycoside of Rubrofusarin, is a protein tyrosine phosphatase 1B (PTP1B) inhibitor with the IC₅₀ of 87.36 μM. Rubrofusarin 6-O-β-D-glucopyranoside can be used for the research of comorbid diabetes and depression.

Cassiaside B, a naphthopyrone, has potent antimicrobial activity.

Obtusinaphthalenside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia has physiological functions related to neuroprotection, anti-inflammation, and hepatoprotection.

Obtusichromoneside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia possesses various physiological functions, including neuroprotection, anti-inflammatory effects, and hepatoprotection.

(3R)-Cassialactone 9-O-β-gentiobioside is a novel naphtholactone glycoside compound that can be isolated from the seeds of Cassia obtusifolia. The natural source plant of (3R)-Cassialactone 9-O-β-gentiobioside belongs to the Cassia genus and has traditional tonic and preventative effects.

Obtusichromoneside A is a chromone C-glycoside glycoside found in the Cassia obtusifolia seeds.

Obtusichromoneside C is a chromone C-glycoside found in the seeds of Cassia obtusifolia. Obtusichromoneside C regulates substance transport by inhibiting substrate uptake of specific transporters (e.g., OAT3, OATP1B3). Obtusichromoneside C is promising for research of drug transport.

Cassiaside C2 is a naphthopyrone with a strong antiallergic activity. Cassiaside C2 inhibits the histamine release from rat peritoneal exudate mast cells induced by antigen-antibody reaction.

2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia.

Pirimiphos ethyl (Standard) is the analytical standard of Pirimiphos ethyl. This product is intended for research and analytical applications. Pirimiphos ethyl is a kind of organophosphorus pesticide that commonly employes for the protection of crops including vegetables, bananas, turf and mushrooms through the inhibition of acetylcholinesterase activity.

Torososide B is an antiallergic compound that inhibits calcium ionophore A-induced leukotriene release from rat peritoneal mast cells.

OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage.

OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage.

6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds.

Xanrhorin is an anthraquinone agent.

4-O-Methylepisappanol (compound 9) is nature product that could be isolated from heartwood of Caesalpinia sappan. 4-O-Methylepisappanol is a potent neuraminidase inhibitor on the surface of influenza viruses with IC₅₀ values of 42.8, 63.2, and 63.2 µM for A/Chicken/Korea/MS96/96 [H9N2], A/PR/8/34 [H1N1], and A/Hong Kong/8/68 [H3N2], respectively.