- Natural Products
- Plants
- Gentianaceae
- Swertia mussotii Franch.
Swertia mussotii Franch.
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Swertia mussotii Franch. (5)
- Formula: C29H30O14
- Molecular Weight: 602.54
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells.
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- Formula: C16H14O6
- Molecular Weight: 302.28
Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes.
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- Formula: C25H28O14
- Molecular Weight: 552.48
α-Glucosidase-IN-70 (compound 9) is an α-glucosidase inhibitor (IC50=31.1 μM) isolated from the traditional Chinese herbal medicine Swertia mussotii. α-Glucosidase-IN-70 can be used in the research of diabetes.
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- Formula: C27H32O16
- Molecular Weight: 612.53
1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone (Compound 18) is a natural product that can be isolated from Swertia mussotii.
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- Formula: C23H28O12
- Molecular Weight: 496.46
Swertiaside is a natural product, that can be isolated from Swertia mussotii Franch.
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