1. Signaling Pathways
  2. Apoptosis
  3. IAP
  4. cIAP-1 Isoform
  5. cIAP-1 Degrader

cIAP-1 Degrader

cIAP-1 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-151966
    TD1092 is a pan-IAP degrader, degrades cIAP1, cIAP2, and XIAP. TD1092 activates Caspase 3/7, and promotes cancer cells apoptosis via IAP degradation. TD1092 inhibits TNFα mediated NF-κB pathway and reduces the phosphorylation of IKK, IkBα, p65, and p38. TD1092 can act as PROTAC, and is used for cancer research.