2. Signaling Pathways
  3. NF-κB
  4. IKK
  5. IKK Isoform
  6. IKK Degrader

IKK Degrader

IKK Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-P1098B
    Ac2-26 ammonium
    		Degrader
    Ac2-26 ammonium is the N-terminal peptide of annexin 1, and has anti-inflammatory activity. Ac2-26 ammonium induces a decrease in IKKβ protein in lysosomes by chaperone-mediated autophagy (CMA). Ac2-26 ammonium ameliorates lung ischemia-reperfusion injury. Ac2-26 ammonium also inhibits airway inflammation and hyperresponsiveness in an asthma rat model.