Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1735):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W005388

(S)-2-(Methylamino)-3-phenylpropanoic acid
(S)-2-(Methylamino)-3-phenylpropanoic acid is a phenylalanine derivative.

HY-W013850

H-D-Lys(Z)-OH		99.65%
H-D-Lys(Z)-OH is a lysine derivative.

HY-W011703

Z-Asp-OH		99.02%
Z-Asp-OH is an aspartic acid derivative.

HY-W041862

Boc-Gly-OMe		99.86%
Boc-Gly-OMe is a Glycine (HY-Y0966) derivative.

HY-W008486

Boc-Phe(4-Cl)-OH		99.75%
Boc-Phe(4-Cl)-OH is a phenylalanine derivative.

HY-W041999

H-D-Asp(OMe)-OMe.HCl
H-D-Asp(OMe)-OMe.HCl is an aspartic acid derivative.

HY-W014692

Boc-D-2,3-diaminopropionic acid
Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine) is an amino acid derivative with a Boc protecting group, which can be used to synthesize a potent NMDA receptor glycine site agonist with GluN2 subunit-specific activity.

HY-W345421

L-γ-Glutamyl-p-nitroanilide hydrate		99.26%
L-γ-Glutamyl-p-nitroanilide (hydrate) is aglutamic acid derivatives.

HY-W015926

H-N-Me-Ala-OH		98.0%
H-N-Me-Ala-OH is an alanine derivative.

HY-W009008

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine		99.52%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine is a cysteine derivative.

HY-W010850

Fmoc-D-Phe(3,4-DiCl)-OH		98.98%
Fmoc-D-Phe(3,4-DiCl)-OH is a phenylalanine derivative.

HY-W020826

S-Phenylcysteine		98.80%
S-Phenylcysteine is acysteine derivatives.

HY-W013293

Boc-D-Tyr-OH		99.56%
Boc-D-Tyr-OH is a tyrosine derivative.

HY-W009262

N-Benzyloxycarbonyl-L-glutamic acid 1-methyl ester		99.87%
N-Benzyloxycarbonyl-L-glutamic acid 1-methyl ester is a glutamic acid derivative.

HY-W048730

Fmoc-Phe(4-tBu)-OH		99.94%
Fmoc-Phe(4-tBu)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize rOicPaPhe(p-Me)-NH(2) with platelet aggregation activation inhibitory activity.

HY-30232

L-Glutamate-γ-benzyl ester		99.88%
L-Glutamate-γ-benzyl ester is a glutamic acid derivative.

HY-W074914

N-Fmoc-5,5,5-trifluoro-L-norvaline		98.77%
N-Fmoc-5,5,5-trifluoro-L-norvaline is an amino acid derivative that can be used for compound synthesis.

HY-P2386

Fmoc-Ala-Ser(psi(Me,Me)pro)-OH		99.67%
Fmoc-Ala-Ser(psi(Me,Me)pro)-OH is a dipeptide.

HY-N10477

gamma-Glutamylarginine
gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine), an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng.

HY-W089230

Boc-His(Boc)-OH
Boc-His(Boc)-OH (N,N'-Di-tert-butoxycarbonyl-L-histidine) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize the dodecapeptide α-mating factor of Saccharomyces cerevisiae.

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