1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. mGluR
  4. mGluR1 Isoform
  5. mGluR1 Inhibitor

mGluR1 Inhibitor

mGluR1 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-101845
    Inhibitor 99.85%
    FITM is a negative allosteric modulator of mGlu1 receptor with a Ki of 2.5 nM.
  • HY-100405
    FTIDC is an orally active, noncompetitive, selective allosteric metabotropic glutamate receptor (mGluR) 1 antagonist with an IC50 of 5.8 nM for human mGluR1a. FTIDC has no species differences in its antagonistic activity on recombinant human, mouse, and rat mGluR1.
  • HY-100404
    Inhibitor 99.04%
    DFMTI can completely block the rmGlu1 L757V glutamate response.