2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (29569):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-150150F
    Cy3-siRNA Negative Control
    		Control
    Cy3-siRNA Negative Control is Cy3-labeled SiRNA Negative Control (HY-150150). Cy3-siRNA Negative Control can be used for easy visualization and assessment of transfection efficiency.
    Cy3-siRNA Negative Control
  • HY-RS12950
    SIRT6 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SIRT6 Human Pre-designed siRNA Set A contains three designed siRNAs for SIRT6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SIRT6 Human Pre-designed siRNA Set A
  • HY-RS09357
    NLRP3 Human Pre-designed siRNA Set A
    		Pre-designed Set

    NLRP3 Human Pre-designed siRNA Set A contains three designed siRNAs for NLRP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    NLRP3 Human Pre-designed siRNA Set A
  • HY-RS13591
    SOX2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SOX2 Human Pre-designed siRNA Set A contains three designed siRNAs for SOX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SOX2 Human Pre-designed siRNA Set A
  • HY-RS04289
    EIF6 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EIF6 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EIF6 Human Pre-designed siRNA Set A
  • HY-RS12349
    RUNX1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    RUNX1 Human Pre-designed siRNA Set A contains three designed siRNAs for RUNX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    RUNX1 Human Pre-designed siRNA Set A
  • HY-RS10483
    PIEZO1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    PIEZO1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIEZO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PIEZO1 Human Pre-designed siRNA Set A
  • HY-132596
    Tivanisiran
    Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA.
    Tivanisiran
  • HY-RS02218
    Cd274 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Cd274 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd274 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Cd274 Mouse Pre-designed siRNA Set A
  • HY-RS09246
    Nfe2l2 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Nfe2l2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nfe2l2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Nfe2l2 Mouse Pre-designed siRNA Set A
  • HY-RS14004
    Sucnr1 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Sucnr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sucnr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Sucnr1 Mouse Pre-designed siRNA Set A
  • HY-RS06058
    HDAC1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    HDAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for HDAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    HDAC1 Human Pre-designed siRNA Set A
  • HY-RS09092
    NCOA4 Human Pre-designed siRNA Set A
    		Pre-designed Set

    NCOA4 Human Pre-designed siRNA Set A contains three designed siRNAs for NCOA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    NCOA4 Human Pre-designed siRNA Set A
  • HY-RS14420
    TFEB Human Pre-designed siRNA Set A
    		Pre-designed Set

    TFEB Human Pre-designed siRNA Set A contains three designed siRNAs for TFEB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TFEB Human Pre-designed siRNA Set A
  • HY-RS01225
    ATP6V1B2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ATP6V1B2 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP6V1B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ATP6V1B2 Human Pre-designed siRNA Set A
  • HY-RS04216
    EGR2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EGR2 Human Pre-designed siRNA Set A contains three designed siRNAs for EGR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EGR2 Human Pre-designed siRNA Set A
  • HY-RS05468
    GLDC Human Pre-designed siRNA Set A
    		Pre-designed Set

    GLDC Human Pre-designed siRNA Set A contains three designed siRNAs for GLDC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GLDC Human Pre-designed siRNA Set A
  • HY-RS05762
    GPT Human Pre-designed siRNA Set A
    		Pre-designed Set

    GPT Human Pre-designed siRNA Set A contains three designed siRNAs for GPT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GPT Human Pre-designed siRNA Set A
  • HY-RS10376
    PGAM5 Human Pre-designed siRNA Set A
    		Pre-designed Set

    PGAM5 Human Pre-designed siRNA Set A contains three designed siRNAs for PGAM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PGAM5 Human Pre-designed siRNA Set A
  • HY-RS00483
    AHR Human Pre-designed siRNA Set A
    		Pre-designed Set

    AHR Human Pre-designed siRNA Set A contains three designed siRNAs for AHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    AHR Human Pre-designed siRNA Set A