Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (16219):

By Effects:	Pre-designed Setss (16156) Inhibitors (9)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-RS14791

TNFAIP8 Human Pre-designed siRNA Set A	Pre-designed Sets
TNFAIP8 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFAIP8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TNFAIP8 Human Pre-designed siRNA Set A TNFAIP8 Human Pre-designed siRNA Set A

HY-RS08353

METTL1 Human Pre-designed siRNA Set A
METTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for METTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

METTL1 Human Pre-designed siRNA Set A METTL1 Human Pre-designed siRNA Set A

HY-RS09944

P4HA3 Human Pre-designed siRNA Set A
P4HA3 Human Pre-designed siRNA Set A contains three designed siRNAs for P4HA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

P4HA3 Human Pre-designed siRNA Set A P4HA3 Human Pre-designed siRNA Set A

HY-RS04472

ERBB4 Human Pre-designed siRNA Set A	Pre-designed Sets
ERBB4 Human Pre-designed siRNA Set A contains three designed siRNAs for ERBB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ERBB4 Human Pre-designed siRNA Set A ERBB4 Human Pre-designed siRNA Set A

HY-132604

Fazirsiran
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes. Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease.

HY-RS03328

CTSD Human Pre-designed siRNA Set A	Pre-designed Sets
CTSD Human Pre-designed siRNA Set A contains three designed siRNAs for CTSD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CTSD Human Pre-designed siRNA Set A CTSD Human Pre-designed siRNA Set A

HY-RS04160

EDF1 Human Pre-designed siRNA Set A	Pre-designed Sets
EDF1 Human Pre-designed siRNA Set A contains three designed siRNAs for EDF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EDF1 Human Pre-designed siRNA Set A EDF1 Human Pre-designed siRNA Set A

HY-132589A

Vutrisiran sodium
Vutrisiran sodium is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran sodium can be used for transthyretin (TTR)-mediated amyloidosis research.

HY-RS09448

NOTCH2 Human Pre-designed siRNA Set A
NOTCH2 Human Pre-designed siRNA Set A contains three designed siRNAs for NOTCH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NOTCH2 Human Pre-designed siRNA Set A NOTCH2 Human Pre-designed siRNA Set A

HY-RS13016

SLC16A1 Human Pre-designed siRNA Set A	Pre-designed Sets
SLC16A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC16A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC16A1 Human Pre-designed siRNA Set A SLC16A1 Human Pre-designed siRNA Set A

HY-RS09579

NRP1 Human Pre-designed siRNA Set A
NRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NRP1 Human Pre-designed siRNA Set A NRP1 Human Pre-designed siRNA Set A

HY-RS09550

NR4A1 Human Pre-designed siRNA Set A
NR4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for NR4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NR4A1 Human Pre-designed siRNA Set A NR4A1 Human Pre-designed siRNA Set A

HY-RS06060

Hdac1 Rat Pre-designed siRNA Set A	Pre-designed Sets
Hdac1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hdac1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hdac1 Rat Pre-designed siRNA Set A Hdac1 Rat Pre-designed siRNA Set A

HY-RS05137

Fto Mouse Pre-designed siRNA Set A	Pre-designed Sets
Fto Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fto gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fto Mouse Pre-designed siRNA Set A Fto Mouse Pre-designed siRNA Set A

HY-RS13608

SP5 Human Pre-designed siRNA Set A	Pre-designed Sets
SP5 Human Pre-designed siRNA Set A contains three designed siRNAs for SP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SP5 Human Pre-designed siRNA Set A SP5 Human Pre-designed siRNA Set A

HY-RS16223

Fdx1 Rat Pre-designed siRNA Set A	Pre-designed Sets
Fdx1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fdx1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fdx1 Rat Pre-designed siRNA Set A Fdx1 Rat Pre-designed siRNA Set A

HY-RS16221

Nphs1 Mouse Pre-designed siRNA Set A	Pre-designed Sets
Nphs1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nphs1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nphs1 Mouse Pre-designed siRNA Set A Nphs1 Mouse Pre-designed siRNA Set A

HY-RS02772

CLDN4 Human Pre-designed siRNA Set A	Pre-designed Sets
CLDN4 Human Pre-designed siRNA Set A contains three designed siRNAs for CLDN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CLDN4 Human Pre-designed siRNA Set A CLDN4 Human Pre-designed siRNA Set A

HY-RS00210

ACSS1 Human Pre-designed siRNA Set A	Pre-designed Sets
ACSS1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACSS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ACSS1 Human Pre-designed siRNA Set A ACSS1 Human Pre-designed siRNA Set A

HY-RS01188

ATP1B3 Human Pre-designed siRNA Set A	Pre-designed Sets
ATP1B3 Human Pre-designed siRNA Set A contains three designed siRNAs for ATP1B3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ATP1B3 Human Pre-designed siRNA Set A ATP1B3 Human Pre-designed siRNA Set A

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