2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. ACV1

ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs.

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ACV1 Chemical Structure

ACV1 Chemical Structure

CAS No. : 740980-24-9

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ACV1 Related Antibodies

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Description

ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. ACV1 is ~100-fold less potent on human α9α10 vs. rat nAChRs[1].

IC50 & Target

IC50: 19 nM (α9α10 nAChR), 140 nM (α6/α3β2β3), 980 nM (α6/α3β4)[1]
Molecular Weight

1806.98

Formula

C71H103N23O25S4
CAS No.
Sequence

Met-Gly-Met-Arg-Met-Met-Phe-Thr-Val-Phe-Leu-Leu-Val-Val-Leu-Ala-Thr-Thr-Val-Val-Ser-Ser-Thr-Ser-Gly-Arg-Arg-Glu-Phe-Arg-Gly-Arg-Asn-Ala-Ala-Ala-Lys-Ala-Ser-Asp-Leu-Val-Ser-Leu-Thr-Asp-Lys-Lys-Arg-Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Asn-Tyr-Asp-His-Pro-Glu-Ile-Cys-Gly
Sequence Shortening

MGMRMMFTVFLLVVLATTVVSSTSGRREFRGRNAAAKASDLVSLTDKKRGCCSDPRCNYDHPEICG
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ACV1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ACV1740980-24-9Vc1.1ACV 1ACV-1nAChRNicotinic acetylcholine receptorsα9α10 nAChR antagonistα-ConotoxinInhibitorinhibitorinhibit

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