2. Anti-infection
  3. Fungal
  4. Efungumab

Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC).

For research use only. We do not sell to patients.

Efungumab Chemical Structure

Efungumab Chemical Structure

CAS No. : 762260-74-2

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Efungumab Related Antibodies

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Description

Efungumab is a monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab can be used for research on invasive candidiasis (IC)[1].

In Vivo

Efungumab (2 mg/kg, i.p., daily for 3 days) significantly decreases mean organ colony counts and increases negative liver biopsies for many of the isolates in CD1 mice models of disseminated c. albicans disease[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD1 mice models of disseminated c. albicans disease[2]
Dosage: 2 mg/kg, daily for 3 days
Administration: Intraperitoneal injection (i.p.)
Result: Decreased mean organ colony counts and increased negative liver biopsies for many of the isolates.
Clinical Trial
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SMILES

[Efungumab]
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Efungumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Efungumab762260-74-2Fungalmonoclonal antibodyantifungalinvasive candidiasis (IC)Inhibitorinhibitorinhibit

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