SLC38A5 - solute carrier family 38 member 5 Gene

Homo sapiens

Also known as SN2; JM24; SNAT5; pp7194

Gene ID: 92745 | Gene type: protein coding

About SLC38A5

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:48,458,544-48,470,260 (from NCBI)

This gene has 13 transcripts (splice variants), 218 orthologues and 15 paralogues. Broad expression in pancreas (RPKM 19.9), bone marrow (RPKM 15.5) and 18 other tissues.

Summary

The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged Amino acids, imino acids, or N-alkylated Amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Aug 2013]

SLC38A5 Products(1)

mRNA	Protein	Name
NM_033518.4	NP_277053.2	sodium-coupled neutral amino acid transporter 5

SLC38A5 Protein Structure

Aa_trans

0
100
200
300
400
472 a.a.

Protein Preferred Names

Protein Names

sodium-coupled neutral amino acid transporter 5

solute carrier family 38 (amino acid transporter), member 5

Related Diseases

Diseases

Alias

Hepatic Encephalopathy

Encephalopathy, Hepatic	Portal-Systemic Encephalopathy
Hepatoencephalopathy	He - [Hepatic Encephalopathy]
Hepatic Encephalopathy Nos	Hepatic Encephalopathy, Stage Unspecified
Hepatic Coma	Hepatocerebral Encephalopathy
Hepatocerebral Intoxication

Mahvash Disease

Gcgr-Related Hyperglucagonemia	MVAH
Alpha-Cell Hyperplasia With Glucagonemia	Nesidioblastosis, Alpha Cell Hyperplasia, Microglucagonoma, And Nonfunctioning Islet Cell Tumor
Nesidioblastosis Alpha Cell Hyperplasia Microglucagonoma And Nonfunctioning Islet Cell Tumor

Brain Edema

Cerebral Edema	Intracranial Swelling
Wet Brain

Osteogenesis Imperfecta, Type Iv

Osteogenesis Imperfecta Type 4	Osteogenesis Imperfecta Type Iv
OI4	Oi, Type Iv
Osteogenesis Imperfecta With Normal Sclerae	Oi Type Iv
Oi Type 4	Osteogenesis Imperfecta With Normal Sclera
Common Variable Oi With Normal Sclerae	Osteogenesis Imperfecta 4
Oi-Iv

Osteogenesis Imperfecta, Type Iii

Osteogenesis Imperfecta Type Iii	OI3
Oi, Type Iii	Osteogenesis Imperfecta Type 3
Oi Type Iii	Oi Type 3
Progressive Deforming Osteogenesis Imperfecta	Severe Osteogenesis Imperfecta
Osteogenesis Imperfecta, Progressively Deforming, With Normal Sclerae	Progressively Deforming Osteogenesis Imperfecta With Normal Sclera
Osteogenesis Imperfecta, Progressively Deforming With Normal Sclerae	Progressively Deforming Oi
Osteogenesis Imperfecta 3	Oi-Iii
Progressively Deforming Osteogenesis Imperfecta With Normal Sclerae

Iminoglycinuria

Iminoglycinuria, Digenic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13223	SLC38A5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SLC38A5	MGD	MGI:2148066
Bos taurus	SLC38A5	VGNC	VGNC:34852
Felis catus	SLC38A5	VGNC	VGNC:65348
Canis familiaris	SLC38A5	VGNC	VGNC:54601
Rattus norvegicus	SLC38A5	RGD	RGD:620702
Macaca mulatta	SLC38A5	VGNC	VGNC:77505

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