2. 疾患モデリングル製品
  3. Cancer Models
  4. Skin Cancer Models

Skin Cancer Models

Skin Cancer Models (4):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-W011845
    DMBA

    DMBA

    		57-97-6 99.94%
    DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
    DMBA
  • HY-107377
    Benzo[a]pyrene

    ベンゾ[a]ピレン

    		50-32-8 99.98%
    Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
    Benzo[a]pyrene
  • HY-W010098
    Terephthalic acid

    テレフタル酸

    		100-21-0 99.99%
    Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models.
    Terephthalic acid
  • HY-115760
    Okadaic acid ammonium salt 175522-42-6 99.9%
    Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation.
    Okadaic acid ammonium salt