2. Academic Validation
  3. HIV-Inhibitory prenylated xanthones and flavones from Maclura tinctoria

HIV-Inhibitory prenylated xanthones and flavones from Maclura tinctoria

  • J Nat Prod. 2000 Nov;63(11):1537-9. doi: 10.1021/np000175m.
A Groweiss 1,  J H Cardellina,  M R Boyd
Affiliations

Affiliation

  • 1 Laboratory of Drug Discovery Research and Development, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, Frederick Cancer Research and Development Center, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
PMID: 11087602 DOI: 10.1021/np000175m
Abstract

The organic extract of the plant Maclura tinctoria exhibited moderate anti-HIV activity. Seven prenylated phenolic derivatives were isolated from the active fractions and characterized by spectroanalytical methods. New compounds macluraxanthone B (1), macluraxanthone C (2), and dihydrocudraflavone B (8) were identified.

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