2. Academic Validation
  3. N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase

N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase

  • Bioorg Med Chem Lett. 2001 Mar 26;11(6):845-8. doi: 10.1016/s0960-894x(01)00077-4.
C Audouin 1,  N Mestdagh,  M A Lassoie,  R Houssin,  J P Hénichart
Affiliations

Affiliation

  • 1 Institut de Chimie Pharmaceutique Albert Lespagnol, Université de Lille 2, France.
PMID: 11277534 DOI: 10.1016/s0960-894x(01)00077-4
Abstract

N-Aminoindoline derivatives were prepared and their 5-lipoxygenase inhibitory activities were evaluated in vitro and compared with those of phenidone and NDGA. Compound 4 presents the most effective 5-LO inhibition.

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