2. Academic Validation
  3. New lysophosphatidylcholines and monoglycerides from the marine sponge Stelletta sp

New lysophosphatidylcholines and monoglycerides from the marine sponge Stelletta sp

  • J Nat Prod. 2003 May;66(5):725-8. doi: 10.1021/np0300075.
Qingchun Zhao 1,  Tayyab A Mansoor,  Jongki Hong,  Chong-O Lee,  Kwang Sik Im,  Dong Seok Lee,  Jee H Jung
Affiliations

Affiliation

  • 1 College of Pharmacy, Pusan National University, Busan 609-735, Korea.
PMID: 12762820 DOI: 10.1021/np0300075
Abstract

Two new lysophosphatidylcholines (1, 2) and four new monoglycerides (5-8) were isolated from the marine Sponge Stelletta sp. by bioactivity-guided fractionation. The planar structures of the new compounds were established on the basis of NMR and MS analyses. The stereochemistry was defined by comparison of the optical rotation. The compounds were evaluated for cytotoxicity against a small panel of five human tumor cell lines.

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