2. Academic Validation
  3. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells

Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells

  • Bull Exp Biol Med. 2003 Jun;135(6):590-2. doi: 10.1023/a:1025493705728.
V Kh Khavinson 1,  I E Bondarev,  A A Butyugov
Affiliations

Affiliation

  • 1 St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of Russian Academy of Medical Sciences. [email protected]
PMID: 12937682 DOI: 10.1023/a:1025493705728
Abstract

Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of Telomerase, and telomere elongation, which can be due to reactivation of Telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.

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