2. Academic Validation
  3. Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

Synthesis and antiviral activity against Coxsackie virus B3 of some novel benzimidazole derivatives

  • Bioorg Med Chem Lett. 2005 Jan 17;15(2):267-9. doi: 10.1016/j.bmcl.2004.10.087.
Jun Cheng 1,  Jiangtao Xie,  Xianjin Luo
Affiliations

Affiliation

  • 1 School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, Shanghai 200240, PR China.
PMID: 15603937 DOI: 10.1016/j.bmcl.2004.10.087
Abstract

Some benzimidazole derivatives were synthesized and evaluated for their Antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B(3) in VERO cells. Some structure-activity relationships were discussed.

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