2. Academic Validation
  3. The phytoalexins from cauliflower, caulilexins A, B and C: isolation, structure determination, syntheses and antifungal activity

The phytoalexins from cauliflower, caulilexins A, B and C: isolation, structure determination, syntheses and antifungal activity

  • Phytochemistry. 2006 Jul;67(14):1503-9. doi: 10.1016/j.phytochem.2006.05.020.
M Soledade C Pedras 1,  Mohammed G Sarwar,  Mojmir Suchy,  Adewale M Adio
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK, Canada S7N 5C9. [email protected]
PMID: 16806330 DOI: 10.1016/j.phytochem.2006.05.020
Abstract

Our continuous search for phytoalexins from crucifers led us to examine phytoalexin production in florets of cauliflower (Brassica oleracea var. botrytis) under abiotic (UV LIGHT) elicitation. Four known (isalexin, S-(-)-spirobrassinin, 1-methoxybrassitin, brassicanal C) and three new (caulilexins A-C) phytoalexins were isolated. The syntheses and Antifungal activity of caulilexins A-C against the economically important pathogenic fungi Leptosphaeria maculans, Rhizoctonia solani and Sclerotinia sclerotiorum, and the first synthesis of brassicanal C are reported.

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