2. Academic Validation
  3. Organosilicon molecules with medicinal applications

Organosilicon molecules with medicinal applications

  • J Med Chem. 2013 Jan 24;56(2):388-405. doi: 10.1021/jm3010114.
Annaliese K Franz 1,  Sean O Wilson
Affiliations

Affiliation

  • 1 Department of Chemistry, University of California-Davis , One Shields Avenue, Davis, California, USA. [email protected]
PMID: 23061607 DOI: 10.1021/jm3010114
Abstract

The incorporation of silicon and synthesis of organosilicon small molecules provide unique opportunities for medicinal applications. The biological investigation of organosilicon small molecules is particularly interesting because of differences in their chemical properties that can contribute to enhanced potency and improved pharmacological attributes. Applications such as inhibitor design, imaging, drug release technology, and mapping inhibitor binding are discussed.

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