2. Academic Validation
  3. Angiosarcoma: A rare malignancy with protean clinical presentations

Angiosarcoma: A rare malignancy with protean clinical presentations

  • J Surg Oncol. 2015 Jun;111(8):941-50. doi: 10.1002/jso.23918.
Justin T Huntington 1,  Christian Jones 2,  David A Liebner 3 4,  James L Chen 3 4,  Raphael E Pollock 5
Affiliations

Affiliations

  • 1 Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
  • 2 Department of Surgery, Division of Trauma, Critical Care and Burn, The Ohio State University Wexner Medical Center, Columbus, Ohio.
  • 3 Division of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
  • 4 Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
  • 5 Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center - James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
PMID: 26031299 DOI: 10.1002/jso.23918
Abstract

Angiosarcoma is a rare form of soft tissue sarcoma. Primary small intestinal angiosarcomas are especially uncommon. The clinical presentations of small intestinal angiosarcomas vary but gastrointestinal (GI) bleeding is a frequent finding. We present a case of persistent GI bleeding of unknown etiology culminating in operative exploration demonstrating a primary small intestinal angiosarcoma. A discussion of the diagnosis, pathology, and management of angiosarcoma with a review of the current literature is provided including molecular genetics, difficult cases, and current treatment options.

Keywords

angiosarcoma; gastrointestinal bleeding; sarcoma; small bowel bleeding.

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