2. Academic Validation
  3. Phenolics from strawberry cv. Falandi and their antioxidant and α-glucosidase inhibitory activities

Phenolics from strawberry cv. Falandi and their antioxidant and α-glucosidase inhibitory activities

  • Food Chem. 2016 Mar 1:194:857-63. doi: 10.1016/j.foodchem.2015.08.091.
Dan Yang 1,  Haihui Xie 2,  Yueming Jiang 3,  Xiaoyi Wei 3
Affiliations

Affiliations

  • 1 Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China; University of Chinese Academy of Sciences, 19A Yuquanlu, Beijing 100049, China.
  • 2 Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China. Electronic address: [email protected].
  • 3 Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, 723 Xingke Road, Tianhe District, Guangzhou 510650, China.
PMID: 26471628 DOI: 10.1016/j.foodchem.2015.08.091
Abstract

Three new phenolic glucosides, falandiosides A (1), B (2), and C (6) were isolated from strawberry (Fragaria×ananassa Duch.) cv. Falandi fruit, together with three flavone glucuronides (3-5), eleven lignan glycosides (12-22), and five Others. Their structures were determined by spectroscopic methods. All the known phenolics were reported from strawberry for the first time. They were evaluated for antioxidant and α-glucosidase inhibitory activities. Three new and fifteen known phenolics showed potent 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical cation scavenging activity with IC50 values of 22.50-4.28μM in comparison to l-ascorbic acid (14.21μM). Quercetin 3-(6-methylglucuronide) (4), (+)-isolariciresinol 9'-glucoside (12), and (-)-isolariciresinol 9'-glucoside (13) were active in scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Moreover, compounds 12 and 13 had moderate ferric reducing antioxidant power (FRAP) values. Further, two new and seven known phenolics exhibited more potent α-glucosidase inhibitory activity with IC50 values of 537.43-25.39μM than acarbose (619.94μM).

Keywords

(+)-Isolariciresinol 9′-glucoside (PubChem CID: 180275); Antioxidant activity; Aviculin (PubChem CID: 10391477); Cedrusin (PubChem CID: 384679); Phenolic compounds; Strawberry; Structure determination; Trichocarpin (PubChem CID: 442989); α-Glucosidase inhibitory activity.

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