Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator

  • Cell. 2018 Apr 5;173(2):286-287. doi: 10.1016/j.cell.2018.03.045.
Libo Shan  1 ,  Ping He  2
Affiliations
  • 1. Department of Plant Pathology and Microbiology and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA. Electronic address: [email protected].
  • 2. Department of Biochemistry and Biophysics and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, USA. Electronic address: [email protected].
PMID: 29625046 DOI: 10.1016/j.cell.2018.03.045
Abstract

The non-protein amino acid pipecolic acid (Pip) is a lysine catabolite involved in plant systemic acquired resistance (SAR). In this issue of Cell, Hartmann et al. (2018) demonstrate that a flavin-dependent monooxygenase converts Pip to N-hydroxypipecolic acid (NHP), which functions as a critical metabolic regulator of SAR in Arabidopsis.

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