2. Academic Validation
  3. Homologous cell membrane-based hydrogel creates spatiotemporal niches to improve outcomes of dysregulated chronic wound healing

Homologous cell membrane-based hydrogel creates spatiotemporal niches to improve outcomes of dysregulated chronic wound healing

  • Mater Today Bio. 2024 Sep 14:28:101243. doi: 10.1016/j.mtbio.2024.101243.
Yijuan Ding 1,  Qi Jia 1,  Ziwen Su 1,  Heying Chen 1,  Jialing Ye 1,  Dafeng Xie 1,  Yubo Wu 1,  Haiyan He 1,  Yanlin Peng 1,  Yilu Ni 1
Affiliations

Affiliation

  • 1 The M.O.E. Key Laboratory of Laboratory Medical Diagnostics, The College of Laboratory Medicine, Chongqing Medical University, #1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, China.
PMID: 39315394 DOI: 10.1016/j.mtbio.2024.101243
Abstract

The (M2M + TGF-β)@HAMA hydrogel dressing improves the outcomes of dysregulated chronic wound healing by protecting the open wound from repeated Bacterial infections, reprogramming endogenous monocytes and M1 macrophages into an M2-phenotype, as well as enhancing fibroblastic proliferation and migration for matrix remodeling and granulation tissue formation.Image 1.

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