2. Academic Validation
  3. 2(S)-((3,5-bis(trifluoromethyl)benzyl)-oxy)-3(S)-phenyl-4- ((3-oxo-1,2,4-triazol-5-yl)methyl)morpholine (1): a potent, orally active, morpholine-based human neurokinin-1 receptor antagonist

2(S)-((3,5-bis(trifluoromethyl)benzyl)-oxy)-3(S)-phenyl-4- ((3-oxo-1,2,4-triazol-5-yl)methyl)morpholine (1): a potent, orally active, morpholine-based human neurokinin-1 receptor antagonist

  • J Med Chem. 1996 Apr 26;39(9):1760-2. doi: 10.1021/jm950654w.
J J Hale 1,  S G Mills,  M MacCoss,  S K Shah,  H Qi,  D J Mathre,  M A Cascieri,  S Sadowski,  C D Strader,  D E MacIntyre,  J M Metzger
Affiliations

Affiliation

  • 1 Merck Research Laboratories, Rahway, New Jersey 07065, USA.
PMID: 8627597 DOI: 10.1021/jm950654w
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