2. Academic Validation
  3. Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds

Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds

  • J Nat Prod. 1997 Nov;60(11):1082-7. doi: 10.1021/np970069t.
F Orsini 1,  F Pelizzoni,  L Verotta,  T Aburjai,  C B Rogers
Affiliations

Affiliation

  • 1 Dipartimento di Chimica Organica e Industriale, Università degli Studi, Milano, Italy. [email protected]
PMID: 9392877 DOI: 10.1021/np970069t
Abstract

Resveratrol 3-O-beta-D-glucopyranoside (1) has been isolated from the seeds of Erythrophleum lasianthum (Caesalpinioidae, Leguminosae), a South African plant used in traditional medicine, and has shown antiplatelet aggregation activity. The synthesis of 1, related hydroxystilbenes, and their glucosides has been undertaken to provide larger quantities, for further biological evaluation, and has been accomplished via Wittig reactions followed by glucosylation under phase transfer catalysis.

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