1. Stem Cell/Wnt
  2. Notch
  3. Notch inhibitor 1

Notch inhibitor 1 

Cat. No.: HY-12860
Handling Instructions

Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer.

For research use only. We do not sell to patients.

Notch inhibitor 1 Chemical Structure

Notch inhibitor 1 Chemical Structure

CAS No. : 1584647-27-7

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Description

Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].

IC50 & Target

IC50: 7.8 nM (Notch 1), 8.5 nM (Notch 3)[1]

In Vitro

Notch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway[1].

Molecular Weight

574.49

Formula

C₂₆H₂₅F₇N₄O₃

CAS No.

1584647-27-7

SMILES

O=C(N[[email protected]@H]1C(NC2=C(C)C=CC=C2C(C3=CC=CC(F)=C3)=N1)=O)[[email protected]](CCC(F)(F)F)[[email protected]](CCC(F)(F)F)C(N)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Notch inhibitor 1
Cat. No.:
HY-12860
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