CCR8 Protein, Macaca fascicularis (Cell-Free, His, SUMO)

CCR8 is part of the G-protein coupled receptor 1 family. CCR8 Protein, Macaca fascicularis (Cell-Free, His, SUMO) is the recombinant cynomolgus-derived CCR8 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of CCR8 Protein, Macaca fascicularis (Cell-Free, His, SUMO) is 355 a.a., with molecular weight of 54.0 kDa.

CCR8, also known as C-C chemokine receptor type 8, is a member of the G-protein coupled receptor 1 (GPCR1) family. GPCRs constitute a diverse family of cell surface receptors that play pivotal roles in signal transduction across the cell membrane. Specifically, CCR8 is involved in mediating the effects of chemokines, which are small proteins that regulate immune cell trafficking and function. As a GPCR, CCR8 is characterized by its seven-transmembrane domains, and upon ligand binding, it activates intracellular signaling cascades, influencing cellular responses. CCR8 is associated with the recruitment and activation of immune cells, participating in inflammatory and immune processes. Understanding the function and regulation of CCR8 can offer insights into immune system modulation and may have implications in various physiological and pathological conditions.

Cynomolgus

E. coli Cell-free

N-6*His;N-SUMO

G7NYJ2 (M1-L355)

102132857

MDYTLDPSMTTMTDYYYPDSLSSPCDGELIQRNDKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRNITDIYLLNLALSDLLFVFSFPFQTYYQLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYAIKVRTIRMGTTLSLVVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFEMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLNYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSHIFIYLGRQMPRESCEKSSSCQQHSFRSSSIDYIL

54.0 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.