1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CXC Chemokines
  5. IP-10/CXCL10
  6. CXCL10 Protein, Cynomolgus (His)

CXCL10 Protein, Cynomolgus (His)

Cat. No.: HY-P700980
Handling Instructions

CXCL10 protein acts as a chemotactic factor for monocytes and T-lymphocytes, playing a crucial role in their migration in response to inflammatory signals. Through binding to CXCR3, CXCL10 selectively attracts monocytes and T-lymphocytes, positioning it as a key player in immune responses, contributing to the recruitment and activation of these immune cells in various physiological and pathological contexts. CXCL10 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived CXCL10 protein, expressed by E. coli , with N-His labeled tag. The total length of CXCL10 Protein, Cynomolgus (His) is 65 a.a., with molecular weight of 12-14 kDa.

For research use only. We do not sell to patients.

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Description

CXCL10 protein acts as a chemotactic factor for monocytes and T-lymphocytes, playing a crucial role in their migration in response to inflammatory signals. Through binding to CXCR3, CXCL10 selectively attracts monocytes and T-lymphocytes, positioning it as a key player in immune responses, contributing to the recruitment and activation of these immune cells in various physiological and pathological contexts. CXCL10 Protein, Cynomolgus (His) is the recombinant cynomolgus-derived CXCL10 protein, expressed by E. coli , with N-His labeled tag. The total length of CXCL10 Protein, Cynomolgus (His) is 65 a.a., with molecular weight of 12-14 kDa.

Background

CXCL10 protein serves as a chemotactic factor for both monocytes and T-lymphocytes, playing a crucial role in orchestrating their migration in response to inflammatory signals. Through its binding to CXCR3, CXCL10 establishes a molecular interaction that facilitates its chemoattraction functions. This selective chemotaxis for monocytes and T-lymphocytes positions CXCL10 as a key player in the immune response, contributing to the recruitment and activation of these immune cells within various physiological and pathological contexts.

Species

Cynomolgus

Source

E. coli

Tag

N-His

Accession

XP_005555067.1 (T27-K91)

Gene ID

102134351  [NCBI]

Molecular Construction
N-term
His
CXCL10 (T27-K91)
Accession # XP_005555067.1
C-term
Synonyms
C-X-C motif chemokine 10; IP-10; CXCL10(1-73); CXCL10; INP10; SCYB10; C7; crg-2; gIP-10; IFI10;
Molecular Weight

12-14 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CXCL10 Protein, Cynomolgus (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CXCL10 Protein, Cynomolgus (His)
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HY-P700980
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