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2131089-46-6

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Area
  • HY-P99777
    Ontorpacept

    TTI-621

    		 Inhibitory Antibodies Cancer
    Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity .

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