Copy Link Print Information

Ontorpacept

(Synonyms: TTI-621)
1 Cited Publications
Customer Review

Based on 1 publication(s) in Google Scholar

Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity.

For research use only. We do not sell to patients.

  • Purity: 99.57%
  • CAS No.: 2131089-46-6
  • Molecular Weight:76.43 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ontorpacept
  • Experimental Validation Results for Ontorpacept
  • Ontorpacept Chemical Structure
    Ontorpacept Chemical Structure
CAS No.: 2131089-46-6
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Ontorpacept Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Ontorpacept

More
Keywords
100 mg

Get Quote In-stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, SIRP, SIRPalpha)-IGHG1 (Fc (Fragment constant)

  • 1/16

    Immobilized Ontorpacept can bind Human CD47 Protein (ECD, His Tag). The EC50 for this effect is 9.12 ng/mL.

  • Ontorpacept Chemical Structure
    1/16
  • Ontorpacept
  • Immobilized Ontorpacept can bind Human CD47 Protein (ECD, His Tag). The EC50 for this effect is 9.12 ng/mL.
  • Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, SIRP, SIRPalpha)-IGHG1 (Fc (Fragment constant)