2131089-46-6
2131089-46-6
Chemical Structure
Ontorpacept
Synonym(s): TTI-621
- CAS No.: 2131089-46-6
- Formula:N/A
- Molecular Weight:(76.43 kDa)
SMILES: [Ontorpacept]
Biological Activity: Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity[1].
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Ontorpacept | 99.57% | Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity. | ||||||||||||||||||||
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References
Keywords
