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Targets Recommended: ULK RAD51

Results for "287405-51-0" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-119307
    Apratastat

    MMP TNF Receptor Cancer
    Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) . Apratastat can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively.