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Results for "

BC-12

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119514
    BC12

    		Phosphodiesterase (PDE) Interleukin Related Inflammation/Immunology
    BC12 is a barbituric acid derivative and a phosphodiesterase 7 (PDE7) inhibitor, with an IC50 of 0.77 μM against human targets. BC12 inhibits the enzymatic activity of PDE7, but this activity is not the driver of its immunomodulatory effects on T lymphocytes. BC12 blocks the upregulation of IL-2 transcription in activated T cells. BC12 modulates the transcriptional response of T cells upon stimulation, exerting anti-inflammatory and pro-stress effects. BC12 inhibits the proliferation of primary mouse T cells and the IL-2 secretion of human peripheral blood T lymphocytes. BC12 exerts immunosuppressive and immunomodulatory effects on T lymphocyte function. BC12 can be used in research related to T lymphocyte-mediated diseases .
    BC12
  • HY-123590
    BC12-4

    		Interleukin Related Inflammation/Immunology
    BC12-4 is a potent IL-2 secretion inhibitor with immunomodulatory activity .
    BC12-4
  • HY-RS05960
    H2BC12 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    H2BC12 Human Pre-designed siRNA Set A contains three designed siRNAs for H2BC12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    H2BC12 Human Pre-designed siRNA Set A
    H2BC12 Human Pre-designed siRNA Set A

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