1. Search Result
Search Result
Results for "

Bubr1 Inhibitors

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100591
    2 Publications Verification

    Sirtuin Neurological Disease Inflammation/Immunology Cancer
    SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140 nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1 .
  • HY-13649
    1 Publications Verification

    ZIO 301; D 24851

    Microtubule/Tubulin Apoptosis Neurological Disease Cancer
    Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis .

Inquiry Online

Your information is safe with us. * Required Fields.



Country or Region *

Applicant Name *


Organization Name *

Department *


Email Address *


Product Name *

Cat. No.


Requested quantity *

Phone Number *



Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
MCE Japan Authorized Agent: