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CD36

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  • HY-P74302
    CD36 Protein, Rat (HEK293, His)

    Platelet glycoprotein 4; GPIIIB; GPIV; CD36; Fat

    		 Rat HEK293
    CD36, a versatile glycoprotein, acts as a receptor for various ligands, including thrombospondin, collagen, and oxidized LDL. Its multivalent ligands induce CD36 clusters, initiating signal transduction. CD36's roles span angiogenesis, inflammation, fatty acid metabolism, and taste perception. It facilitates fatty acid transport, influencing muscle utilization, adipose storage, and gut absorption. Mechanistically, it activates LYN kinase, leading to CD36 depalmitoylation and endocytosis. In the small intestine, CD36 aids dietary absorption through MAPK1/3 signaling. It also regulates oral fat perception, hypothalamic function, and contributes to antiangiogenic and inflammatory effects. Additionally, CD36 selectively senses microbial lipopeptides, triggering cytokine production via TLR2:TLR6 heterodimer signaling. CD36 Protein, Rat (HEK293, His) is the recombinant rat-derived CD36 protein, expressed by HEK293, with C-His labeled tag. The total length of CD36 Protein, Rat (HEK293, His) is 410 a.a., with molecular weight of 70-80 kDa.
  • HY-P74303
    CD36 Protein, Rat (HEK293, Fc)

    Platelet glycoprotein 4; GPIIIB; GPIV; CD36; Fat

    		 Rat HEK293
    CD36 is a multifunctional glycoprotein that serves as a receptor for a variety of ligands, including thrombospondin, collagen, and oxidized low-density lipoprotein. Its multivalent ligand induces CD36 clusters, initiating signal transduction. CD36 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD36 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD36 Protein, Rat (HEK293, Fc) is 410 a.a., with molecular weight of ~108 kDa.

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