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Results for "

COX-2-IN-6

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115866
    COX-2-IN-6

    		COX Cancer
    COX-2-IN-6 (compound 10) is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. COX-2-IN-6 selectively targets COX-2 with an IC50 of 0.84 μM and a Ki of 69 nM. COX-2-IN-6 also inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM .
    <em>COX-2-IN-6</em>
  • HY-N0710
    alpha-Cyperone
    2 Publications Verification

    α-Cyperone; (+)-α-Cyperone

    		 Endogenous Metabolite Inflammation/Immunology
    alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.
    alpha-Cyperone
  • HY-N8413
    Chlojaponilactone B

    		Toll-like Receptor (TLR) Reactive Oxygen Species NF-κB Inflammation/Immunology
    Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α .
    Chlojaponilactone B

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