1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. alpha-Cyperone

alpha-Cyperone (Synonyms: α-Cyperone; (+)-α-Cyperone)

Cat. No.: HY-N0710 Purity: 99.12%
Handling Instructions

alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

For research use only. We do not sell to patients.

alpha-Cyperone Chemical Structure

alpha-Cyperone Chemical Structure

CAS No. : 473-08-5

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5 mg USD 60 In-stock
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10 mg USD 96 In-stock
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25 mg USD 216 In-stock
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50 mg USD 384 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

The anti-inflammatory activity of alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells[1].
alpha-Cyperone (α-Cyperone) binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter[2].

Molecular Weight

218.33

Formula

C₁₅H₂₂O

CAS No.

473-08-5

SMILES

O=C1C(C)=C2C[[email protected]](C(C)=C)CC[[email protected]@]2(C)CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

References

Purity: 99.12%

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Keywords:

alpha-Cyperoneα-Cyperone(+)-α-CyperoneEndogenous MetaboliteInhibitorinhibitorinhibit

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alpha-Cyperone
Cat. No.:
HY-N0710
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