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CSF3R

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P700725
    G-CSFR/CD114 Protein, Mouse (HEK293, His)

    G-CSF-R; G-CSF R; CD114; G CSF R; CSF3R; CSFgr; GCSFR

    		 Mouse HEK293
    G-CSFR/CD114 Protein, functioning as the receptor for granulocyte colony-stimulating factor (CSF3), plays a pivotal role in granulocyte development and function. As a homodimer, it binds two CSF3 molecules, transducing signals. G-CSFR/CD114's interaction with CEACAM1 down-regulates the CSF3R-STAT3 pathway, recruiting PTPN6 for dephosphorylation, revealing regulatory roles in modulating granulocyte colony-stimulating factor responses. These interactions emphasize G-CSFR/CD114's intricate regulatory involvement in immune responses and hematopoiesis. G-CSFR/CD114 Protein, Mouse (HEK293, His) is the recombinant mouse-derived G-CSFR/CD114 protein, expressed by HEK293, with C-His labeled tag. The total length of G-CSFR/CD114 Protein, Mouse (HEK293, His) is 601 a.a., with molecular weight of 90-110 kDa.

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