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Dofetilide

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0232
    Dofetilide
    2 Publications Verification

    UK 68789

    		 Potassium Channel Cardiovascular Disease
    Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease .
    <em>Dofetilide</em>
  • HY-B0232S
    Dofetilide-d4

    UK 68789 D4
    Dofetilide-d4 is a deuterium labeled Dofetilide. Dofetilide is a class III antiarrhythmic agent.
    <em>Dofetilide</em>-d4
  • HY-100623
    Dofetilide N-oxide

    UK-116856

    		 Potassium Channel Cardiovascular Disease
    Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels .
    <em>Dofetilide</em> N-oxide
  • HY-B0232R
    Dofetilide (Standard)

    UK 68789 (Standard)

    		 Potassium Channel Cardiovascular Disease
    Dofetilide (Standard) is the analytical standard of Dofetilide. This product is intended for research and analytical applications. Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease .
    <em>Dofetilide</em> (Standard)
  • HY-116759
    VU0405601

    		Potassium Channel Cardiovascular Disease
    VU0405601 is a potent KV11.1 channel activator. VU0405601 protects cardiac tissue from dofetilide (HY-B0232)-induced ventricular tachycardia .
    VU0405601
  • HY-16915
    RPR-260243
    1 Publications Verification

    		 Potassium Channel Cardiovascular Disease
    RPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel . RPR-260243 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    RPR-260243

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