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Cat. No.: HY-100623

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Dofetilide N-oxide

(Synonyms: UK-116856)

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels.

For research use only. We do not sell to patients.

CAS No.: 144449-71-8
Formula: C₁₉H₂₇N₃O₆S₂
Molecular Weight:457.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Dofetilide N-oxide Chemical Structure

CAS No.: 144449-71-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
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Biological Activity

Description

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels^[1]^[2].

IC₅₀ & Target

Potassium channels^[1]^[2]

Chemical Information

CAS No. 144449-71-8
Molecular Weight 457.56
Formula C₁₉H₂₇N₃O₆S₂
SMILES

CS(=O)(NC1=CC=C(CC[N+](CCOC2=CC=C(NS(=O)(C)=O)C=C2)(C)[O-])C=C1)=O
Synonyms

UK-116856
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Maisch B, et al. Pregnancy and cardiomyopathies. Herz. 2003 May;28(3):196-208. [Content Brief]

[2]. Snyders, D.J. and A. Chaudhary, High affinity open channel block by dofetilide of HERG expressed in a human cell line. Mol Pharmacol, 1996. 49(6): p. 949-55. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Mabuterol (Standard)

Quinaprilat (Standard)

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(17R,18S)-Epoxyeicosatetraenoic acid

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Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dofetilide N-oxide

Quinaprilat

Mabuterol

3-O-Methyl-DL-DOPA

Acebutolol

3-O-Methyl-DL-DOPA (Standard)

7-Hydroxywarfarin

Hydroxymetronidazole

Mabuterol (Standard)

Quinaprilat (Standard)

Wy-45494 hydrochloride (Standard)

(17R,18S)-Epoxyeicosatetraenoic acid

Wy-45494 hydrochloride

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dofetilide N-oxide Related Classifications

HY-100623 Related Classifications