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HAVCR1

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  • HY-P71365
    TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His)

    Hepatitis A virus cellular receptor 1 homolog; HAVCR-1; Kidney injury molecule 1; KIM-1; T cell membrane protein 1; TIM-1

    		 Mouse HEK293
    The TIM-1/KIM-1/HAVCR protein is a phosphatidylserine receptor that is critical for B cell homeostasis, affecting generation, expansion, and inhibitory functions. As a P-selectin/SELPLG ligand, it facilitates trafficking of activated T cells during inflammation and controls T cell accumulation in the inflamed central nervous system. TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, C-His) is 191 a.a., with molecular weight of 35-50 kDa.
  • HY-P73603
    TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His)

    Hepatitis A virus cellular receptor 1; HAVCR-1; KIM-1; TIM-1; CD365; HAVCR1

    		 Mouse HEK293
    TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) belongs to a family of immunoglobulin-like domain-containing transmembrane proteins is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. TIM1 (HAVCR1) facilitates attachment of a variety of enveloped viruses, including filoviruses, alphaviruses, and flaviviruses, that display highly conserved phosphatidylserine (PtdSer) on their surface. TIM1 undergoes tyrosine phosphorylation of its C-terminal cytoplasmic tail. TIM-1 can function as a co-stimulatory molecule for T cell activation. TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) is the recombinant mouse-derived TIM-1/KIM-1/HAVCR protein, expressed by HEK293 , with N-His labeled tag. The total length of TIM-1/KIM-1/HAVCR Protein, Mouse (HEK293, His) is 191 a.a., with molecular weight of ~23 kDa.

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