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Results for "

Mca-SEVNLDAEFK(Dnp)

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

9

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P4920
    Mca-SEVNLDAEFK(Dnp)-NH2

    		Fluorescent Dye Others
    Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .
    <em>Mca-SEVNLDAEFK</em>(Dnp)-NH2
  • HY-P4919
    Mca-SEVNLDAEFK(Dnp)

    		Beta-secretase Others
    Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.
    <em>Mca-SEVNLDAEFK</em>(Dnp)
  • HY-P1729
    M-2420

    		Fluorescent Dye Neurological Disease
    M-2420 is a fluorogenic substrate containing β-secretase site of the Swedish mutation of amyloid precursor protein (APP) .
    M-2420
  • HY-P5905
    Citrullinated amyloid-β (1-42) peptide (human)

    Citrullinated Aβ (1-42); Citrullinated Aβ42

    		 Amyloid-β Neurological Disease
    Citrullinated amyloid-β (1-42) peptide (human) (Citrullinated Aβ (1-42)) is a modified form of β-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified β-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified Aβ42, it forms protofibrils comprised of parallel β-sheets .
    Citrullinated amyloid-β (1-42) peptide (human)
  • HY-P5906
    Citrullinated amyloid-β (1-40) peptide (human)

    Citrullinated Aβ (1-40); Citrullinated Aβ40

    		 Amyloid-β Neurological Disease
    Citrullinated amyloid-β (1-40) peptide (human) (Citrullinated Aβ (1-40)) is a modified form of β-Amyloid (1-40) (HY-P0265) with a citrullination at the Arg5 site. Citrullinated amyloid-β (1-40) peptide (human) exhibits increased transient formation of soluble oligomers and insoluble aggregates composed of distorted parallel β-sheets compared with unmodified β-Amyloid (1-40) .
    Citrullinated amyloid-β (1-40) peptide (human)
  • HY-P4899
    RE(EDANS)EVNLDAEFK(DABCYL)R

    		Beta-secretase Neurological Disease
    RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .
    RE(EDANS)<em>EVNLDAEFK</em>(DABCYL)R

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