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Cat. No.: HY-P4899

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β-Secretase substrate VI, fluorogenic

(Synonyms: RE(EDANS)EVNLDAEFK(DABCYL)R)

β-Secretase substrate VI, fluorogenic is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). β-Secretase substrate VI, fluorogenic can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction.

For research use only. We do not sell to patients.

CAS No.: 310427-94-2
Formula: C₉₁H₁₂₉N₂₅O₂₅S
Molecular Weight:2005.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

β-Secretase substrate VI, fluorogenic Chemical Structure

CAS No.: 310427-94-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 310427-94-2
Molecular Weight 2005.22
Formula C₉₁H₁₂₉N₂₅O₂₅S
Synonyms

RE(EDANS)EVNLDAEFK(DABCYL)R
Sequence

Arg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg
Sequence Shortening

R-{Glu(EDANS)}-EVNLDAEF-{Lys(DABCYL)}-R
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

β-Secretase substrate VI, fluorogenic

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Biological Activity
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β-Secretase substrate VI, fluorogenic

All Beta-secretase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

β-Secretase substrate VI, fluorogenic Related Classifications

HY-P4899 Related Classifications