β-Secretase inhibitor
Based on 1 Customer Validation
β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase).
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 350228-37-4
- Formula: C73H118N16O27
- Molecular Weight:1651.81
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* The compound is unstable in solutions, freshly prepared is recommended.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PC-12 | IC50 |
0.03 μM
Compound: 22
|
Inhibition of human brain beta-secretase, using MBPC125Swe (maltose-binding-protein C-125 Swedish) assay
Inhibition of human brain beta-secretase, using MBPC125Swe (maltose-binding-protein C-125 Swedish) assay
|
[PMID: 11784130] |
Chemical Information
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CAS No. 350228-37-4
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Appearance Solid
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Molecular Weight 1651.81
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Formula C73H118N16O27
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Color White to off-white
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Synonyms
[Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)
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Sequence
Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe
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Sequence Shortening
KTEEISEVN-{Sta}-VAEF
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * The compound is unstable in solutions, freshly prepared is recommended.
Purity & Documentation
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Data Sheet (259 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)