1. Signaling Pathways
  2. Neuronal Signaling
  3. Beta-secretase
  4. BACE2 Isoform

BACE2

 

BACE2 Related Products (3):

Cat. No. Product Name Effect Purity
  • HY-16759
    Verubecestat
    Inhibitor 99.56%
    Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease.
  • HY-136742
    BACE2-IN-1
    Inhibitor 99.34%
    BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes.
  • HY-12938
    AMG-8718
    Inhibitor
    AMG-8718 is a potent, selective and orally active BACE1 inhibitor with IC50 values of 0.0007, 0.005 µM for BACE1 and BACE2, respectively. AMG-8718 significantly decreases Aβ40 levels in the CSF and brain.