BACE1-IN-14
BACE1-IN-14 (compound 27f) is a BACE1 inhibitor, with the EC50 values of 0.7 μM and 1.6 μM for BACE1 and BACE2. BACE1-IN-14 is can be used in Alzheimer's disease (AD) research.
For research use only. We do not sell to patients.
- Formula: C26H20FN3O
- Molecular Weight:409.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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BACE1 0.7 μM (EC50) |
BACE2 1.6 μM (EC50) |
Chemical Information
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Molecular Weight 409.45
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Formula C26H20FN3O
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SMILES
FC1=CC(NC(NC2=C(COC3=CC=C(C4=CC=CC=C4)C=C3)C=CC=C2)=N5)=C5C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BACE1-IN-14 Related Classifications
HY-161359 Related Classifications
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