1. Neuronal Signaling
  2. Beta-secretase
  3. Verubecestat

Verubecestat (Synonyms: MK-8931)

Cat. No.: HY-16759 Purity: 99.79%
Handling Instructions

Verubecestat (MK-8931) is a beta-secretase 1 (BACE1) inhibitor under investigation for the treatment of Alzheimer's Disease.

For research use only. We do not sell to patients.

Verubecestat Chemical Structure

Verubecestat Chemical Structure

CAS No. : 1286770-55-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 88 In-stock
Estimated Time of Arrival: December 31
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
25 mg USD 240 In-stock
Estimated Time of Arrival: December 31
50 mg USD 420 In-stock
Estimated Time of Arrival: December 31
100 mg USD 620 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Verubecestat (MK-8931) is a beta-secretase 1 (BACE1) inhibitor under investigation for the treatment of Alzheimer's Disease.

Clinical Trial
Molecular Weight

409.41

Formula

C₁₇H₁₇F₂N₅O₃S

CAS No.

1286770-55-5

SMILES

O=C(C1=NC=C(F)C=C1)NC2=CC=C(F)C([[email protected]@](C3)(C)N=C(N)N(C)S3(=O)=O)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 35 mg/mL (85.49 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4425 mL 12.2127 mL 24.4254 mL
5 mM 0.4885 mL 2.4425 mL 4.8851 mL
10 mM 0.2443 mL 1.2213 mL 2.4425 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.79%

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Verubecestat
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HY-16759
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