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Cat. No.: HY-P2714

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SEVNLDAEFR

SEVNLDAEFR is a substrate for BACE1.

For research use only. We do not sell to patients.

CAS No.: 186142-28-9
Formula: C₅₀H₇₈N₁₄O₁₉
Molecular Weight:1179.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SEVNLDAEFR Chemical Structure

CAS No.: 186142-28-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

SEVNLDAEFR is a substrate for BACE1^[1].

IC₅₀ & Target

BACE1^[1]

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 186142-28-9
Molecular Weight 1179.24
Formula C₅₀H₇₈N₁₄O₁₉
Sequence

Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg
Sequence Shortening

SEVNLDAEFR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer's disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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SEVNLDAEFR

β-Amyloid (1-16)

β-Amyloid (1-11)

β-Amyloid (1-15)

β-Secretase substrate VI, fluorogenic

β-Amyloid (1-40) (rat)

Amyloid β-Protein (1-46)

β-Amyloid precursor protein (96-110), cyclized (human)

Amyloid β-Protein (1-6)

Amyloid β-Protein (1-12)

Amyloid β-Protein (16-22)

(Val2)-Amyloid β-Protein (1-6)

Acetyl-Amyloid β-Protein (1-6) amide

All Beta-secretase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

SEVNLDAEFR

β-Amyloid (1-16)

β-Amyloid (1-11)

β-Amyloid (1-15)

β-Secretase substrate VI, fluorogenic

β-Amyloid (1-40) (rat)

Amyloid β-Protein (1-46)

β-Amyloid precursor protein (96-110), cyclized (human)

Amyloid β-Protein (1-6)

Amyloid β-Protein (1-12)

Amyloid β-Protein (16-22)

(Val2)-Amyloid β-Protein (1-6)

Acetyl-Amyloid β-Protein (1-6) amide

All Beta-secretase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SEVNLDAEFR Related Classifications

HY-P2714 Related Classifications

Bioz