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  3. Fluorescent Dye
  4. Mca-SEVNLDAEFK(Dnp)-NH2

Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1.

For research use only. We do not sell to patients.

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Mca-SEVNLDAEFK(Dnp)-NH2 Chemical Structure

Mca-SEVNLDAEFK(Dnp)-NH2 Chemical Structure

CAS No. : 1802078-32-5

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Based on 1 publication(s) in Google Scholar

Mca-SEVNLDAEFK(Dnp)-NH2 Related Antibodies

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Description

Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1[1].

Molecular Weight

1532.52

Formula

C68H89N15O26
CAS No.
Appearance

Solid

Color

Light yellow to yellow

Sequence

{Mca}-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(Dnp)}-NH2
Sequence Shortening

{Mca}-SEVNLDAEF-{Lys(Dnp)}-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 1.25 mg/mL (0.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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Mca-SEVNLDAEFK(Dnp)-NH2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mca-SEVNLDAEFK(Dnp)-NH21802078-32-5Fluorescent DyeFluorescent substrateactivities of peptidasesactivity of BACE-1Inhibitorinhibitorinhibit

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Mca-SEVNLDAEFK(Dnp)-NH2
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HY-P4920
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