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Rosuvastatin-<sub>13</sub>C,d<sub>3</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17504BS2
    Rosuvastatin-13C,d3 sodium

    ZD 4522-<sub>13sub>C,d<sub>3sub> sodium; X-Plended-<sub>13sub>C,d<sub>3sub> sodium; Crestor-<sub>13sub>C,d<sub>3sub> sodium

    		 Autophagy Bacterial HMG-CoA Reductase (HMGCR) Potassium Channel Isotope-Labeled Compounds Cardiovascular Disease Metabolic Disease
    Rosuvastatin- 13C,d3 sodium is 13C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM . Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
    Rosuvastatin-13C,d3 sodium

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